Endocrine Abstracts

Introduction: Acromegaly is characterized by high cardiovascular morbidity and mortality. Oxidative stress and endothelial dysfunction are underlying mechanisms of atherosclerosis. The aim of this study was to evaluate the blood redox status and endothelial function by means of nitric oxide (NO) levels in patients with acromegaly.Description of methods/design: Total antioxidant capacity (TAC), catalase activity and glutathione concentration (GSH), as mea...

Introduction: Antithyroid drugs (ATD) remain the first-line therapy in patients with Graves’ disease (GD), despite high relapse rate. The purpose of the present study was to identify predictors of long term remission of GD in patients who received ATD as primary treatment.Description of methods/design: We restrospectively identified patients with Graves’ disease initially treated with ATD between 1984 and 2011 and extracted relevant data from t...